Biotech SF: Pfizer, Bristol-Myers Squibb to fund study of Portola's blood-thinner antidote

Portola CEO Bill Lis.

Portola Pharmaceuticals Inc. will get an undisclosed amount of cash in a deal with Bristol-Myers Squibb Co. and Pfizer Inc. to test its experimental treatment to reverse the effect of blood-thinning Factor Xa inhibitor drugs, the company said Thursday.

The antidote, called PRT-4445, is supposed to reverse the anticoagulation work of so-called Factor Xa inhibitors, including Eliquis from Bristol-Myers Squibb (NYSE: BMY) and Pfizer (NYSE: PFE) and South San Francisco-based Portola's betrixaban.

Some of my favorite stories.

• "The fight of his life" (2007)

Last year Mike Homer helped raise the money for 2,000 medical research computers. Now researchers are using that equipment in an attempt to save his life.

• "For reporter, CJD is more than a story" (2007)

Seven years ago -- nearly to the day -- my mother died of Creutzfeld-Jakob Disease.

• "A son's YouTube plea for Avastin" (2010)

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• "New device could knock out old dialysis technology" (2011)

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All he needs now is $20 million.

Biotech SF

Thursday, November 1, 2012

Pfizer, Bristol-Myers Squibb to fund study of Portola's blood-thinner antidote

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