Showing posts with label Alios. Show all posts
Showing posts with label Alios. Show all posts

Friday, December 9, 2011

Vertex, Alios start early-stage hepatitis C trials on 2 drugs

Alios BioPharma Inc. and partner Vertex Pharmaceuticals Inc. said Friday that they started two early-stage studies on separate hepatitis C drugs.
Alios, based in South San Francisco, and Cambridge, Mass.-based Vertex (NASDAQ: VRTX) said the safety and tolerability studies of ALS-2200 and ALS-2158 will return data in the second quarter of 2012.

Monday, June 13, 2011

Alios lands $60M in hepatitis C licensing deal with Vertex

Vertex Pharmaceuticals Inc. (Nasdaq: VRTX) and Alios BioPharma Inc. on Monday announced a licensing agreement, adding two distinct nucleotide analogues to Vertex’s hepatitis C portfolio. The compounds, discovered by Alios and known as ALS-2200 and ALS-2158, are potential treatments of the hepatitis C virus.
As part of the agreement, Vertex will make an up-front payment of $60 million to South San Francisco-based Alios, in exchange for the worldwide rights to ALS-2200 and ALS-2158. Vertex will take on development costs and research funding, as well as up to $715 million in milestone payments if both compounds are approved. Cambridge, Mass.-based Vertex already expects to pay about $35 million in development milestones in 2011.
Alios is also eligible to receive up to $750 million in sales milestones.